ALLERGEN-SPECIFIC IMMUNOTHERAPY WITH LIPOSOME CONTAINING CPG-ODN IN MURINE MODEL OF ASTHMA RELIES ON MYD88 SIGNALING IN DENDRITIC CELLS

Allergen-Specific Immunotherapy With Liposome Containing CpG-ODN in Murine Model of Asthma Relies on MyD88 Signaling in Dendritic Cells

Changing the immune responses to allergens is the cornerstone of allergen immunotherapy.Allergen-specific immunotherapy that consists of repeated administration of increasing doses of allergen extract is potentially curative.The major inconveniences of allergen-specific immunotherapy include failure to modify immune responses, long-term treatment l

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Randomized, double-blind, placebo-controlled and active-controlled study to assess the relative abuse potential of oxycodone HCl-niacin tablets compared with oxycodone alone in nondependent, recreational opioid users

Lynn R Webster,1 Robert L Rolleri,2,3 Glenn C Pixton,3 Kenneth W Sommerville31Lifetree Clinical Research, Salt Lake City, UT, USA; 2Salix Pharmaceuticals, Inc., Raleigh, NC, USA; 3Pfizer Inc, Cary, NC, USABackground: Abuse-deterrent formulations attempt to address public health and societal concerns regarding opioid abuse.Oxycodone HCl-niacin table

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Cepheids with the eyes of photometric space telescopes

Space Eyelashes photometric missions have been steadily accumulating observations of Cepheids in recent years, leading to a flow of new discoveries.In this short review we summarize the findings provided by the early missions such as WIRE, MOST, and CoRoT, and the recent results of the Kepler and K2 missions.The surprising and fascinating results f

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